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OpenResponses due Oct 7, 2026, 2:00 PM EDT

Organ system modeling in outer space research

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening, Solicitation ARPA-H-SOL-26-165, issued by Federal (District of Columbia offices).

Official posting and documentsfree with an account

At a glance

ARPA-H is seeking innovative research solutions for comprehensive organ system modeling experiments in outer space through the COSMOS program. This federal research solicitation is open to qualified organizations and is due October 7, 2026.

Key facts

Solicitation number
ARPA-H-SOL-26-165
Portal id
7fb62afa210e4e209bb0110a6ea477eb
Type
Solicitation
Posted
Sep 21, 2026
Response deadline
Oct 7, 2026, 2:00 PM EDT
Place of performance
DC
Official posting
Documents, addenda and the procurement contact, free with an account.
  • research and development
  • biotechnology
  • space research
  • organ modeling
  • federal grants

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Official description

The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement. Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165 Amendment 01 – 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal. Questions and Answers – 21 September 2026: This Q&A is provided for informational purposes only and does not amend the solicitation. All other questions are due by 23 September 2026 at 2:00PM ET.

Solicitation #ARPA-H-SOL-26-165. Issued by HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NATIONAL INSTITUTES OF HEALTH › ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H). NAICS 541714. Product/Service Code AN13.

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