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OpenResponses due Oct 18, 2026, 5:00 PM EDT

Systems for phenotypic evaluation clinical trajectories response

Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA), Solicitation ARPA-H-SOL-26-163, issued by Federal (District of Columbia offices).

At a glance

ARPA-H is seeking proposals for Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA), a research initiative to develop advanced systems for evaluating patient phenotypes and clinical outcomes. The work will be performed in Washington, D.C., with proposals due October 18, 2026. This is a scientific research and development opportunity for organizations capable of managing complex healthcare data and clinical evaluation systems.

Key facts

Solicitation number
ARPA-H-SOL-26-163
Portal id
ae0ce5edc4c341afbf26a9413cfdae62
Type
Solicitation
Posted
Sep 17, 2026
Response deadline
Oct 18, 2026, 5:00 PM EDT
Place of performance
DC
Official posting
Documents, addenda and the procurement contact, free with an account.
  • research and development
  • healthcare systems
  • clinical research
  • data analytics
  • phenotypic evaluation

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Official description

SPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time. SPECTRA will also develop technologies that serve two purposes at once: extending reliable assessment beyond the clinic while improving everyday communication, function, and quality of life. The same tools people use to live more fully will also generate the data that drive measurement and personalized care.

Solicitation #ARPA-H-SOL-26-163. Issued by HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NATIONAL INSTITUTES OF HEALTH › ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H). NAICS 541715. Product/Service Code AN13.

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