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OpenResponses due Oct 13, 2026, 12:00 PM EDT

Restorative and health-enhancing sleep time research

Restorative and health-Enhancing Sleep Time (REST), Solicitation ARPA-H-SOL-26-159, issued by Federal (District of Columbia offices).

Official posting and documentsfree with an account

At a glance

ARPA-H is seeking research proposals to investigate sleep's role in health and disease prevention. This federal research solicitation supports innovative projects addressing sleep science and health outcomes. Proposals are due October 13, 2026.

Key facts

Solicitation number
ARPA-H-SOL-26-159
Portal id
9d6ebbcb27514376827ac5c3566cd5b8
Type
Solicitation
Posted
Sep 21, 2026
Response deadline
Oct 13, 2026, 12:00 PM EDT
Place of performance
DC
Official posting
Documents, addenda and the procurement contact, free with an account.
  • research
  • sleep science
  • health
  • federal grant
  • biomedical

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Official description

The Advanced Research Projects Agency for Health (ARPA-H) seeks proposals for the Restorative & health-Enhancing Sleep Time (REST) program, a bold effort to transform how poor sleep is measured and treated by enabling objective, home-based, closed-loop technologies that detect health-relevant sleep microstructures and respond to them in real time. If successful, REST will establish the technical foundation for a new generation of sleep health technologies that are objective, personalized, and capable of improving long-term health outcomes at scale. 6/16: Amendment 1 updates links within the ISO 6/18: Amendment 2 adds Section 6.5 Questions and Answers 6/24: Amendment 3 makes various edits for clarification in Sections 1-3. 7/7: Amendment 4 modifies the table in Section 3.2.1 TA1 Success Metrics. 7/16: Amendment 5 modifies additional text within the table in Section 3.2.1 TA1 Success Metrics. 8/10: Amendment 6 modifies the solicitation by breaking the Solution Summary, Proposal and Pitch into distinct categories. Solution Summaries will be reviewed on an encourage/discourage basis; Proposals will be evaluated on an invite/not invited basis; Pitches will be evaluated on a selected for negotiation/not selected basis. 8/11: Amendment 7 modifies Section 3.3 Key Program Milestones table. Changes made in Amendment 6 remain in red text to highlight important changes to solicitation process. 9/14: Amendment 8 modifies Section 4.4 Proposal Requirements and reactivates solicitation until proposal due date. 9/15: Amendment 9 adds REST Proposal Template folder as an attachment to the solicitation. 9/21: Amendment 10 revises REST Proposal Template document "REST_APPENDIX B.0_Proposal Format and Instructions".

Solicitation #ARPA-H-SOL-26-159. Issued by HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NATIONAL INSTITUTES OF HEALTH › ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H). NAICS 541715. Product/Service Code AN13.

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